[侧脑室肿瘤。回顾284例]。

PubMed ID
发表日期 年月

原始出处 神经外科
Neuro-Chirurgie
作者 Baroncini  M  Peltier  J  Le Gars  D  Lejeune  J-P 

文献标题 [侧脑室肿瘤。回顾284例]。
[Tumors of the lateral ventricle. Review of 284 cases].

文献摘要 UNLABELLED

收集1995年至2010年间法国18个神经外科治疗的284例侧脑室肿瘤的资料。平均年龄33岁,儿童比例大(79/284)。

CLINICAL PRESENTATION

平均症状持续时间短(2个月)。10%的病例是偶然发现的;对于症状性病变,颅内压升高(颅内压,由于脑积水)和神经心理症状是最常见的。只有三分之一的病人没有脑脊液紊乱。

HISTOPATHOLOGY

最常见的两种肿瘤是脑膜瘤(40例,15%)和神经细胞瘤(35例,13%)。室管膜下巨细胞星形细胞瘤、室管膜瘤和室管膜下巨细胞瘤也很常见(分别为11%、10%和9%)。

THERAPEUTIC MANAGEMENT

手术治疗258例,其中1/3的病例在神经导航的帮助下进行。患者最常采用经额入路手术(40%)。手术切除率为73%,这是总生存率的统计因素。术后死亡率为4.9%。

OUTCOME

神经心理缺陷是颅内压升高引起的最常见后遗症(22.8%)。随后发现运动障碍(19%)、癫痫(19%)、偏瘫(15%)和语言障碍(12%)。平均随访52个月,58%的患者进展良好。百分之十五的病人有残疾,最后有百分之十二点九的病人会死。最后,三分之二的患者没有肿瘤残留或复发。


UNLABELLED

The data from 284 cases of lateral ventricle (VL) tumors treated in 18 departments of Neurosurgery in France between 1995 and 2010 were collected in this series. The mean age was 33 years with a large proportion of children (79/284).

CLINICAL PRESENTATION

The mean duration of symptoms was short in time (2 months). The revelation was incidental in 10% of the cases; for symptomatic lesions, raised intracranial pressure (ICP, due to hydrocephalus) and neuropsychological signs were the most frequent. Only one third of the patients had no CSF disorder.

HISTOPATHOLOGY

The two most frequent tumors were meningiomas (40 cases, 15%) and neurocytomas (35 cases, 13%). The sub-ependymal giant cells astrocytomas, the ependymomas and sub-ependymomas were also common (11, 10 and 9% respectively).

THERAPEUTIC MANAGEMENT

A surgical procedure was performed in 258 patients, with the help of neuronavigation in one third of cases. The patients were most frequently operated with a transfrontal approach (40%). The resection was complete in 73%, which was a statistical factor of global survival. The postoperative mortality rate was 4.9%.

OUTCOME

Neuropsychological deficits were the most frequent sequelae (22.8%) due to raised ICP. Campimetric deficits (19%), seizures (19%), hemiparesis (15%) and language disorders (12%) were then found. The mean follow-up was 52 months with good evolution for 58% of patients. Fifteen percent of patients had a handicap and, finally, 12.9% will die. At last, two third of living patients had no tumoral residue or re-evolution.


获取全文 10.1016/j.neuchi.2011.09.020