红景天治疗身心疲劳的系统评价。

PubMed ID
发表日期 2012年May月

原始出处 补充和替代医学
BMC complementary and alternative medicine
作者 Ishaque  Sana  Shamseer  Larissa  Bukutu  Cecilia  Vohra  Sunita 

文献标题 红景天治疗身心疲劳的系统评价。
Rhodiola rosea for physical and mental fatigue: a systematic review.

文献摘要 BACKGROUND

红景天(R.rosea)生长在高海拔和北纬地区。由于其所谓的适应特性,它已经被研究在健康人群中的性能增强能力和在许多临床人群中的治疗特性。系统回顾玫瑰果对身心疲劳有效性和安全性的证据。

METHODS

检索6个电子数据库,以确定随机对照试验(RCTs)和对照临床试验(CCTs),评价蔷薇花对身心疲劳的疗效和安全性。两位评审员独立筛选已鉴定的文献,提取数据并评估纳入研究的偏倚风险。

RESULTS

在搜索中确定的206篇文章中,有11篇符合本次审查的入选标准。10个被描述为随机对照试验,1个被描述为有条件现金转移。在健康人群中检测身体疲劳的六个试验中,有两个报告说玫瑰红莓是有效的,五个随机对照试验中有三个评估了蔷薇精神疲劳。所有被纳入的研究要么显示出高风险的偏见,要么报告的缺陷阻碍了对其真实有效性的评估(不清楚的偏差风险)。

CONCLUSION

关于蔷薇果有效性的研究是矛盾的。虽然一些证据表明,这种草药可能有助于提高身体素质和缓解精神疲劳,但方法上的缺陷限制了对疗效的准确评估。一个严格设计的,充分报告的随机对照试验,以尽量减少偏差,以确定真正的有效性玫瑰红疲劳。


BACKGROUND

Rhodiola rosea (R. rosea) is grown at high altitudes and northern latitudes. Due to its purported adaptogenic properties, it has been studied for its performance-enhancing capabilities in healthy populations and its therapeutic properties in a number of clinical populations. To systematically review evidence of efficacy and safety of R. rosea for physical and mental fatigue.

METHODS

Six electronic databases were searched to identify randomized controlled trials (RCTs) and controlled clinical trials (CCTs), evaluating efficacy and safety of R. rosea for physical and mental fatigue. Two reviewers independently screened the identified literature, extracted data and assessed risk of bias for included studies.

RESULTS

Of 206 articles identified in the search, 11 met inclusion criteria for this review. Ten were described as RCTs and one as a CCT. Two of six trials examining physical fatigue in healthy populations report R. rosea to be effective as did three of five RCTs evaluating R. rosea for mental fatigue. All of the included studies exhibit either a high risk of bias or have reporting flaws that hinder assessment of their true validity (unclear risk of bias).

CONCLUSION

Research regarding R. rosea efficacy is contradictory. While some evidence suggests that the herb may be helpful for enhancing physical performance and alleviating mental fatigue, methodological flaws limit accurate assessment of efficacy. A rigorously-designed well reported RCT that minimizes bias is needed to determine true efficacy of R. rosea for fatigue.


获取全文 10.1186/1472-6882-12-70