钩藤中吲哚生物碱及其药理研究进展。

PubMed ID
G H
发表日期 2013年Apr月

原始出处 菲托特拉皮亚
Fitoterapia
作者 Ndagijimana  Andre  Wang  Xiaoming  Pan  Guixiang  Zhang  Fan  Feng  Hong  Olaleye  Olajide 

文献标题 钩藤中吲哚生物碱及其药理研究进展。
A review on indole alkaloids isolated from Uncaria rhynchophylla and their pharmacological studies.
A review on indole alkaloids isolated from Uncaria rhynchophylla and their pharmacological studies.

文献摘要

钩藤(Uncaria rhynchophylla,Miq.)Jacks,茜草科,是钩藤的原植物之一,主要用于治疗惊厥、高血压、癫痫、子痫和脑疾病。这种植物的药理活性与以吲哚生物碱为主的活性化合物的存在有关。本文综述了近年来国内外有关从美国分离的主要吲哚生物碱的药理活性报道。钩藤属。本文对钩藤属药用制剂的化学、安全性及质量控制等方面的研究作一综述。


Uncaria rhynchophylla (Miq.) Jacks, Rubiaceae, is one of the original plants of the important Chinese crude drug, Gou-teng, mainly used for the treatment of convulsion, hypertension, epilepsy, eclampsia, and cerebral diseases. The pharmacological activities of this plant are related to the presence of active compounds predominantly indole alkaloids. In this article, we have reviewed some reports about the pharmacological activities of the main indole alkaloids isolated from U. rhynchophylla. This review paper will contribute to the studies on the chemistry, safety and quality control of medicinal preparations containing Uncaria species.

Uncaria rhynchophylla (Miq.) Jacks, Rubiaceae, is one of the original plants of the important Chinese crude drug, Gou-teng, mainly used for the treatment of convulsion, hypertension, epilepsy, eclampsia, and cerebral diseases. The pharmacological activities of this plant are related to the presence of active compounds predominantly indole alkaloids. In this article, we have reviewed some reports about the pharmacological activities of the main indole alkaloids isolated from U. rhynchophylla. This review paper will contribute to the studies on the chemistry, safety and quality control of medicinal preparations containing Uncaria species.


获取全文 10.1016/j.fitote.2013.01.018