使用沐浴油减少皮肤干燥症状的有效性:一项随机对照实用主义研究。

PubMed ID
G H
发表日期 2017年Jan月

原始出处 国际护理研究杂志
International journal of nursing studies
作者 Kottner  Jan  Kanti  Varvara  Dobos  Gabor  Hahnel  Elisabeth  Lichterfeld-Kottner  Andrea  Richter  Claudia  Hillmann  Kathrin  Vogt  Annika  Blume-Peytavi  Ulrike 

文献标题 使用沐浴油减少皮肤干燥症状的有效性:一项随机对照实用主义研究。
The effectiveness of using a bath oil to reduce signs of dry skin: A randomized controlled pragmatic study.
The effectiveness of using a bath oil to reduce signs of dry skin: A randomized controlled pragmatic study.

文献摘要 BACKGROUND

干性皮肤(皮肤干燥症)越来越被认为是一个相关的健康问题,在日常生活和保健护理。使用洗浴添加剂,如油,是常见的,以减少皮肤干燥,但经验证据支持这一做法是有限的。

OBJECTIVES

本研究的目的是调查使用沐浴油添加剂在改善皮肤屏障功能和改善皮肤干燥方面的效果,并与用于沐浴或淋浴的不含油皮肤清洁剂进行比较。

DESIGN

单中心随机观察者盲语用平行组试验。

SETTINGS

门诊/社区护理。

PARTICIPANTS

从柏林市招募的临床表现为轻度至中度皮肤干燥的志愿者。

METHODS

健康的儿童和成人被随机分配使用市售的沐浴油,或者在28天的研究期内每隔一天继续使用常规的不含油的皮肤清洁剂。在研究中心的基线检查和两次随访中评估皮肤屏障参数和皮肤干燥的严重程度。主要结果是皮肤失水。

RESULTS

所有60名参与者随机完成了试验。中位年龄为32.5岁(IQR 8.3-69)。研究结束时,与对照组相比,干预组的平均经皮皮肤失水量在统计学上显著降低(平均差异-1.9(95%可信区间-3.1至-0.8)g/m2/h)。研究结束时,干预组的角质层水合作用在统计学上显著高于对照组。两组的皮肤表面pH值和粗糙度相当,保持不变,虽然两组都显示出皮肤干燥症状改善的趋势结论:这项务实的试验提供了经验证据,证明在日常皮肤护理中,经常使用所研究的沐浴油可有效改善轻度皮肤干燥的儿童和成人的皮肤屏障功能,并支持将其作为治疗皮肤干燥的基本元素广泛干性皮肤病的治疗。

TRIAL REGISTRATION

临床试验.gov标识符NCT02557698。


BACKGROUND

Dry skin (xerosis cutis) is increasingly recognized as a relevant health problem in daily life and in health and nursing care. The use of bath additives such as oils is common to reduce dry skin, but empirical evidence supporting this practice is limited.

OBJECTIVES

The aim of this study was to investigate the effectiveness of using a bath oil additive in improving skin barrier function and ameliorating dry skin in comparison to non-oil containing skin cleansers for bathing or showering.

DESIGN

Single centre randomized observer blind pragmatic parallel group trial.

SETTINGS

Outpatient/community care.

PARTICIPANTS

Volunteers showing clinically mild to moderate dry skin recruited from the city of Berlin.

METHODS

Healthy children and adults were randomly assigned to use either a commercially available bath oil or to continue using their regular non-oil containing skin cleansers every other day over a study period of 28days. Skin barrier parameters and the severity of dry skin were assessed at baseline and at two follow-up visits at the study centre. Transepidermal water loss was the primary outcome.

RESULTS

All sixty participants randomized completed the trial. Median age was 32.5 (IQR 8.3 to 69) years. At the end of study the mean transepidermal water loss in the intervention group was statistically significant lower compared to the control group (mean difference -1.9 (95% CI -3.1 to -0.8) g/m2/h). Stratum corneum hydration was statistically significantly higher in the intervention group at the end of the study. Skin surface pH and roughness were comparable in both groups and remained unchanged, while both groups showed a trend to improvement in dry skin symptoms CONCLUSIONS: This pragmatic trial provides empirical evidence that the regular use of the investigated bath oil is effective in improving the skin barrier function in children and adults with mild dry skin when used in routine skin care and supports its use as a basic element for the management of a broad spectrum of dry skin conditions.

TRIAL REGISTRATION

ClinicalTrials.gov Identifier NCT02557698.

BACKGROUND

Dry skin (xerosis cutis) is increasingly recognized as a relevant health problem in daily life and in health and nursing care. The use of bath additives such as oils is common to reduce dry skin, but empirical evidence supporting this practice is limited.

OBJECTIVES

The aim of this study was to investigate the effectiveness of using a bath oil additive in improving skin barrier function and ameliorating dry skin in comparison to non-oil containing skin cleansers for bathing or showering.

DESIGN

Single centre randomized observer blind pragmatic parallel group trial.

SETTINGS

Outpatient/community care.

PARTICIPANTS

Volunteers showing clinically mild to moderate dry skin recruited from the city of Berlin.

METHODS

Healthy children and adults were randomly assigned to use either a commercially available bath oil or to continue using their regular non-oil containing skin cleansers every other day over a study period of 28days. Skin barrier parameters and the severity of dry skin were assessed at baseline and at two follow-up visits at the study centre. Transepidermal water loss was the primary outcome.

RESULTS

All sixty participants randomized completed the trial. Median age was 32.5 (IQR 8.3 to 69) years. At the end of study the mean transepidermal water loss in the intervention group was statistically significant lower compared to the control group (mean difference -1.9 (95% CI -3.1 to -0.8) g/m2/h). Stratum corneum hydration was statistically significantly higher in the intervention group at the end of the study. Skin surface pH and roughness were comparable in both groups and remained unchanged, while both groups showed a trend to improvement in dry skin symptoms CONCLUSIONS: This pragmatic trial provides empirical evidence that the regular use of the investigated bath oil is effective in improving the skin barrier function in children and adults with mild dry skin when used in routine skin care and supports its use as a basic element for the management of a broad spectrum of dry skin conditions.

TRIAL REGISTRATION

ClinicalTrials.gov Identifier NCT02557698.


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