[短期角膜塑形术对成人近视眼泪膜的影响]。

PubMed ID
发表日期 2020年Jan月

原始出处 四川大学报。易学班=四川大学学报。医学版
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
作者 Bian  Si-Yu  Renqian  Ge-Mai  He  Yuan-Hao  Wang  Jiang-Lan  Yang  Bi  Liu  Long-Qian 

文献标题 [短期角膜塑形术对成人近视眼泪膜的影响]。
[The Influence of Short-term Orthokeratology on Tear Film in Adult Myope].

文献摘要 Objective

目的探讨成人近视患者短期整夜角膜塑形术后泪膜的变化。

Methods

50名年龄在18至38岁的成年近视患者被纳入本研究。在本研究期间,患者每晚6-10小时佩戴角膜塑形术。分别于术前、术后1d、7d、14d、30d、90d测量无创泪液破裂时间(NITBUT)、荧光泪液破裂时间(FTBUT)、下半月板高度(LTMH)、角膜荧光染色及眼表疾病指数(OSDI)问卷评分。

Results

44名受试者完成了后续研究。整夜配戴角膜塑形术后,泪液破裂时间(TBUT)下降,14d趋于稳定。LTMH持续下降,通宵佩戴90d后差异有显著性(P<0.05)。与基线相比,各时间点角膜染色程度均有所提高(P<0.05)。至于OSDI评分,在所有时间点都没有差异。

Conclusion

整夜配戴角膜塑形术后,泪膜稳定性和泪液分泌减少。成人近视患者夜间配戴角膜塑形术后易发生角膜损伤。


Objective

To study the changes of tear film after short-term overnight orthokeratology wearing in adult myope.

Methods

Fifty adult myope aged 18 to 38 years old were enrolled in this study. The patients wore orthokeratology 6-10 h every night during this study. Data such as non-invasive tear break-up time (NITBUT), fluorescent tear break-up time (FTBUT), lower tear meniscus height (LTMH), corneal fluorescent staining as well as ocular surface disease index (OSDI) questionnaire score were measured at baseline, 1 d, 7 d, 14 d, 30 d and 90 d.

Results

Forty-four subjects completed the follow-up study. Tear break-up time (TBUT) decreased and became stable at 14 d after overnight orthokeratology wearing. LTMH sustained decreased and there was a difference after 90 d overnight wearing ( P<0.05). Compared with baseline, the grade of corneal staining increased at all time points ( P<0.05). As for the OSDI score, there was no difference at all time points.

Conclusion

After overnight orthokeratology wearing, tear film stability and tear secretion decreased. Adult myope seems easily to suffer corneal injury after overnight orthokeratology wearing.


获取全文 10.12182/20200160605