含Djulis的胶原蛋白配方改善皮肤水化、亮度、质地、鱼尾纹和胶原蛋白含量:一项双盲、随机、安慰剂对照试验。

PubMed ID
发表日期 2020年Jun月

原始出处 皮肤美容杂志
Journal of cosmetic dermatology
作者 Lin  Ping  Alexander  Ruth Audy  Liang  Chia-Hua  Liu  Cheng  Lin  Yung-Hao  Lin  Yung-Hsiang  Chan  Leong-Perng  Kuan  Chen-Meng 

文献标题 含Djulis的胶原蛋白配方改善皮肤水化、亮度、质地、鱼尾纹和胶原蛋白含量:一项双盲、随机、安慰剂对照试验。
Collagen formula with Djulis for improvement of skin hydration, brightness, texture, crow's feet, and collagen content: A double-blind, randomized, placebo-controlled trial.

文献摘要 BACKGROUND

Djulis的护肤功效目前是基于细胞或动物模型,临床方面还不到位。

AIM

本研究旨在探讨鱼胶原与台湾藜(Chenopodium formosanum Koidz.)对改善皮肤参数的协同作用。我们利用水解胶原蛋白和朱利斯的结合,开发出一种新的皮肤改善功能配方。

PATIENTS/METHODS

50名志愿者被随机分配(以1:1的比例)到安慰剂或胶原蛋白饮料组。志愿者被要求每天饮用50毫升胶原蛋白饮料或安慰剂饮料,持续8周。测量时,分别在基线检查时、第4周和第8周测量皮肤状况指数。

RESULTS

胶原蛋白组8周后皮肤含水量、白度、鱼尾纹、纹理、皱纹、毛孔、斑点、胶原蛋白含量改善率分别为17.8%、5.4%、14.9%、9.9%、29.3%、10.4%、9.9%和22.3%。值得注意的是,超过68%的受试者在服用胶原蛋白饮料8周后皮肤参数得到改善。与之前的研究相比,这些改善水平表明了具有竞争力的皮肤改善效果。

CONCLUSION

这项临床研究证明了鱼胶原和朱利斯(主要成分)的协同作用,可显著改善皮肤的水化、亮度、鱼尾纹、纹理、皱纹、毛孔、表面斑点和胶原蛋白含量。胶原蛋白饮料全面改善了大多数受试者4周后的皮肤参数,与其他类似研究相比显示出了竞争性的效果。我们相信胶原蛋白饮料可以延缓皮肤老化过程,改善皮肤老化参数。


BACKGROUND

The efficacy of Djulis for skin care is currently based on cellular or animal models, and the clinical aspect is not in place.

AIM

This clinical study is to investigate the synergistic effect of fish collagen and Djulis (Chenopodium formosanum Koidz.) for improvement of skin parameters. We used the combination of hydrolyzed collagen and Djulis to develop a new functional formula for skin improvement.

PATIENTS/METHODS

Fifty volunteers were randomly allocated (in a 1:1 ratio) to the placebo or collagen drink group. Volunteers were required to consume a 50 mL of a collagen drink or placebo drink daily for 8 weeks. For measurements, the indexes of skin conditions were measured at the baseline and 4 and 8 weeks.

RESULTS

The improvements of skin hydration, brightness, crow's feet, texture, wrinkles, pores, spots, and collagen content after 8 weeks in collagen group were 17.8%, 5.4%, 14.9%, 9.9%, 29.3%, 10.4%, 9.9%, and 22.3%, respectively. Noticeably, over 68% of subjects got improved for their skin parameters after 8-week intake of collagen drink. The improvement levels indicated competitive skin improvement effects in comparison with previous studies.

CONCLUSION

This clinical study demonstrates the synergistic effect of fish collagen and Djulis (the main components) for the substantial improvements in hydration, brightness, crow's feet, texture, wrinkles, pores, surface spots, and collagen content in skin. The collagen drink comprehensively improved skin parameters for most subjects after 4-week intake and manifested competitive efficiency in comparison with other similar studies. We convince that the collagen drink may delay skin aging process and improve skin aging parameters.


获取全文 10.1111/jocd.13500