钩藤属:植物化学代谢产物和生物学方面的综述。

PubMed ID
G H
发表日期 2020年Nov月

原始出处 菲特拉皮亚酒店
Fitoterapia
作者 Liang  Jia-Hao  Wang  Chao  Huo  Xiao-Kui  Tian  Xiang-Ge  Zhao  Wen-Yu  Wang  Xun  Sun  Cheng-Peng  Ma  Xiao-Chi 

文献标题 钩藤属:植物化学代谢产物和生物学方面的综述。
The genus Uncaria: A review on phytochemical metabolites and biological aspects.
The genus Uncaria: A review on phytochemical metabolites and biological aspects.

文献摘要

茜草属(茜草科)有34种,其中许多常用作治疗高血压、发热、头痛、胃肠道疾病和真菌感染的中药。近二十年来,乌贼属植物在植物化学和生物学方面受到了广泛的关注,已鉴定出约100种新的次生代谢产物,包括生物碱、三萜和黄酮类化合物。本文综述了钩藤属近二十年来报道的化合物的生物来源、结构及其生物合成途径,以及药理作用。这将为钩藤属植物的新兴药理学应用提供一个视角。


The genus Uncaira (Rubiaceae) comprises of 34 species, many of which are usually used as traditional Chinese medicines (TCMs) to treat hypertension, fever, headache, gastrointestinal illness, and fungal infection. Over the past twenty years, Uncaira species have been paid the considerable attentions in phytochemical and biological aspects, and about 100 new secondary metabolites, including alkaloids, triterpenes, and flavonoids, have been elucidated. This review aims to present a comprehensive and up-to date overview of the biological source, structures and their biosynthetic pathways, as well as the pharmacological of the compounds reported in the genus Uncaria for the past two decades. It would provide an insight into the emerging pharmacological applications of the genus Uncaria.

The genus Uncaira (Rubiaceae) comprises of 34 species, many of which are usually used as traditional Chinese medicines (TCMs) to treat hypertension, fever, headache, gastrointestinal illness, and fungal infection. Over the past twenty years, Uncaira species have been paid the considerable attentions in phytochemical and biological aspects, and about 100 new secondary metabolites, including alkaloids, triterpenes, and flavonoids, have been elucidated. This review aims to present a comprehensive and up-to date overview of the biological source, structures and their biosynthetic pathways, as well as the pharmacological of the compounds reported in the genus Uncaria for the past two decades. It would provide an insight into the emerging pharmacological applications of the genus Uncaria.


获取全文 10.1016/j.fitote.2020.104772