雄激素性脱发的毛发镜检查结果。

PubMed ID
G H
发表日期 2021年Apr月

原始出处 医疗档案(萨拉热窝、波斯尼亚和黑塞哥维那)
Medical archives (Sarajevo, Bosnia and Herzegovina)
作者 Kasumagic-Halilovic  Emina 

文献标题 雄激素性脱发的毛发镜检查结果。
Trichoscopic Findings in Androgenetic Alopecia.
Trichoscopic Findings in Androgenetic Alopecia.

文献摘要 Background

雄激素性脱发(AGA)是一种与雄激素相关的疾病,发生于遗传易感个体。这种情况的特点是头皮上的终末毛发以特征性分布逐渐消失。毛发镜检查代表头皮和头发的皮肤镜检查成像。毛发镜可观察到的结构包括毛干、毛囊开口、毛囊周围表皮和皮肤微血管。

Objective

这项前瞻性研究的目的是确定雄激素性脱发的毛发特征。

Methods

本研究纳入了104名AGA患者和80名健康受试者。收集和分析有关年龄、性别、个人和家族史、临床类型和病程的数据。对照组由80名一般健康的受试者组成。使用视频皮肤镜或手持式皮肤镜进行毛发镜检查。在头皮的额部、枕部和两侧颞部区域获得毛发镜检查结果,包括黄点和软毛的数量、一个皮脂腺单元中的毛发数量以及毛囊周围色素沉着的毛囊口的百分比。对数据进行统计评估。

Results

雄激素性脱发患者的黄点、仅有一根毛发的毛囊皮脂腺单位和毛囊周围色素沉着明显增多(p<0.05)。AGA中的细毛百分比(<0.03 mm)显著高于健康对照组(p<0.05)。

Conclusion

我们的研究表明了毛发镜检查对AGA患者的意义。定期的临床和毛发镜随访对于监测疾病活动和治疗耐受性非常重要。


Background

Androgenetic alopecia (AGA) is an androgen-related condition that develops in genetically predisposed individuals. The condition is characterized by the progressive loss of terminal hairs on the scalp in a characteristic distribution. Trichoscopy represents the dermoscopy imaging of the scalp and hair. Structures which may be visualized by trichoscopy include hair shafts, hair follicle openings, perifollicular epidermis and cutaneous microvessels.

Objective

The aim of this prospective study was to identify the trichoscopic features of androgenetic alopecia.

Methods

Hundred-four patients with AGA and 80 healthy subjects were enrolled in this study. Data on age, gender, personal and family history, clinical type and duration of disease were collected and analyzed. Control group consisted of 80 generally healthy subjects. Trichoscopic examination was performed using either videodermatoscope or handheld dermatoskope. Trichoscopy results were obtained in frontal, occipital and both temporal areas of the scalp, including number of yellow dots and vellus hairs, number of hairs in one pilosebaceous unit and percentage of follicular ostia with perifollicular hyperpigmentation. The data were statistically evaluated.

Results

The number of yellow dots, pilosebaceous units with only one hair and with perifollicular hyperpigmentation was significantly increased in androgenetic alopecia (p<0.05). The percentage of thin hairs (<0.03 mm) in AGA was significantly higher than in healthy controls (p<0.05).

Conclusion

Our study has shown the significances of trichoscopy of patients with AGA. Regular clinical and trichoscopical follow-ups are very important to monitor disease activity and treatment tolerance.

Background

Androgenetic alopecia (AGA) is an androgen-related condition that develops in genetically predisposed individuals. The condition is characterized by the progressive loss of terminal hairs on the scalp in a characteristic distribution. Trichoscopy represents the dermoscopy imaging of the scalp and hair. Structures which may be visualized by trichoscopy include hair shafts, hair follicle openings, perifollicular epidermis and cutaneous microvessels.

Objective

The aim of this prospective study was to identify the trichoscopic features of androgenetic alopecia.

Methods

Hundred-four patients with AGA and 80 healthy subjects were enrolled in this study. Data on age, gender, personal and family history, clinical type and duration of disease were collected and analyzed. Control group consisted of 80 generally healthy subjects. Trichoscopic examination was performed using either videodermatoscope or handheld dermatoskope. Trichoscopy results were obtained in frontal, occipital and both temporal areas of the scalp, including number of yellow dots and vellus hairs, number of hairs in one pilosebaceous unit and percentage of follicular ostia with perifollicular hyperpigmentation. The data were statistically evaluated.

Results

The number of yellow dots, pilosebaceous units with only one hair and with perifollicular hyperpigmentation was significantly increased in androgenetic alopecia (p <0.05). The percentage of thin hairs (<0.03 mm) in AGA was significantly higher than in healthy controls (p<0.05).

Conclusion

Our study has shown the significances of trichoscopy of patients with AGA. Regular clinical and trichoscopical follow-ups are very important to monitor disease activity and treatment tolerance.


获取全文 10.5455/medarh.2021.75.109-111